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Studies have demonstrated that buckwheat ( Fagopyrum esculentum Moench) polysaccharides elevate SCFAs levels, particularly acetic acid, propionic acid, and butyric acid, while enriching SCFA-producing taxa, such as Eubacterium xylanophilum group, Lachnospiraceae NK4A136 group, and Lactobacillus , which shifts consequently attenuate CNS neuroinflammation and oxidative stress, enhance autophagy, reduce AD-related pathological markers, and ultimately improve cognitive deficits in aluminum trichloride-treated rats (Liu et al., 2024)
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